Founded on March 28, 1995 with a vision of creating
a healthier China, we have rapidly evolved from a distributor
of pharmaceutical products into a leading manufacturer
and supplier of drugs in the rapidly growing China pharmaceutical
market. We currently have 6 Good Manufacturing Practices("GMP")-certified
modernized manufacturing bases, 2 nationwide sales
and marketing subsidiaries, 1 research and development
center and total of more than 2,000 employees.
We currently manufacture and sell more than 50 pharmaceutical
products and are the exclusive distributor of three
additional pharmaceutical products marketed under our
brand name, covering a wide range of diseases such as
cancer, cerebrovascular and cardiovascular diseases,
infections, arthritis, diarrhea, allergies, respiratory
conditions and urinary conditions. Our market leading
pharmaceutical products include a stroke management medication,
Bicun, the first synthetic free radical scavenger (edaravone
injection) sold in China; Zailin, a generic amoxicillin
granule antibiotic; an innovative anti-cancer medication,
Endu (also known as “Endostar”), the first
recombinant human endostatin injection approved for
sale in China; Yingtaiqing, a generic diclofenac sodium
sustained-release capsule for inflammation and pain
relief; Anqi, a generic amoxicillin with clavulanate
potassium antibiotic; and Biqi, an OTC generic smectite
powder for diarrhea. These products contributed annual
revenue of more than RMB 800 million in 2006. In addition
to these core products, Simcere Kechuanning, Zaike,
and Faneng each contributed annual revenue of RMB 30
- 40 million in 2006. In addition, China’s State
Food and Drug Administration ("SFDA") has
also granted us approval for the manufacture and sale
of 100 other products.
Our strategic focus is to introduce first-to-market
generic and innovative pharmaceuticals for the treatment
of diseases with high incidence and/or mortality rates
and for which there is a clear demand for more effective
pharmacotherapy, such as our first-to-market generic
stroke management medication Bicun and our anti-cancer medication
Endu (also known as “Endostar”).
In September 2006, Simcere acquired 80% of Shandong
Simcere Medgenn Bio-Pharmaceutical Co., Ltd for RMB
200 million and launched its new patented anti-cancer
drug, Endu (also known as "Endostar"), the
first recombinant human endostatin successfully commercialized
in the world. This purchase was one of the biggest acquisition
cases in China’s pharmaceutical industry targeting
a single pharmaceutical product’s intellectual
property. The successful commercialization of Endu is
a result of joint efforts from our R&D team, led
by Dr. Yongzhang Luo, the independent clinical research
team, headed by Dr. Yan Sun, and our professional sales
and marketing team. Clinical research was conducted
in 24 hospitals in China and an independent specialists
committee audited the clinical research statistics and
data. The results of our Phase III clinical trial on
493 non-small-cell lung cancer ("NSCLC") patients
showed that the Endu-plus-chemotherapy approach provides
an effective alternative for treating NSCLC.
Our goal is to become a leading pharmaceutical company
by providing innovative medicine in China. We believe
constant innovation in research and development is vital
to our long-term competitiveness and success and will
determine the future of the pharmaceutical industry
in China. We will maintain our commitment to investing
in research and development activities while focusing
on innovative products with a high potential for commercialization,
as well as first-to-market generic pharmaceutical products.
Our over 5,000m2 research and development
center in Nanjing provides a solid platform to support
a variety of research activities including synthetic
research, drug analysis and pharmacological and cytological
research. Our post-doctorate research workstation currently
has four research staff and it was certified by the
State Ministry of Human Resources. To supplement our
in-house research and development capabilities, we also
plan to increase our collaborations with domestic and
international pharmaceutical and biotechnology companies
and institutions. Our agreement with Tsinghua University
in February 2006 established a Joint Laboratory for
Drug Discovery to engage in the research and development
of innovative pharmaceuticals. Simcere’s commitment
to research and development helps to ensure a robust
pipeline of product candidates in various stages of
development, including products for the treatment of
cancer, cerebrovascular diseases, infections, rheumatoid
arthritis, nasal allergies and nausea and vomiting associated
with chemotherapy. With our deep knowledge about the
Chinese pharmaceutical market and increasing cooperation
with domestic and international resources, Simcere is
well positioned to provide quality products and services
that will exceed our customers’ expectations and
help us meet the challenges of the new century.
Our employees are valuable business partners and internal
customers, sharing our beliefs and business vision.
Simcere believes every employee’s potential should
be maximized and we are devoted to investing our resources
to ensure their success. A hunger for excellence is
in the blood of every Simcere employee and they strive
to create value for the company to maximize our shareholders’
return while being socially responsible.
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