ENZESHU®:Suvisexumab for Injection

ENZESHU®:Suvisexumab for Injection

Indications:

Suvisexumab, in combination with paclitaxel, liposomal doxorubicin, or topotecan, is indicated for the treatment of adult patients with recurrent platinum-resistant ovarian cancer, fallopian tube cancer, or primary peritoneal cancer who have received no more than one prior line of systemic therapy.

Enzeshu® (Suvisexumab for Injection) is co-developed by Simcere Zaiming and Pyxis Oncology. Simcere Zaiming completed its preclinical and clinical studies, executed cell line screening and process development using proprietary technology platforms, and manufactured clinical trial supplies. Post-approval, commercial production will be conducted at Simcere Zaiming’s antibody facility in Nanjing Jiangbei New Area.

As a recombinant humanized anti-VEGF monoclonal antibody, Enzeshu® exerts antitumor effects by precisely blocking VEGF-receptor binding to inhibit tumor angiogenesis. It is China’s first anti-angiogenic targeted drug approved for the full platinum-resistant ovarian cancer population, transcending the historically limited therapeutic landscape in this field.